Mon Dec 16 11:50:00 UTC 2024: ## USF Study Links Ultra-Processed Foods to Colorectal Cancer, Paving Way for New Therapies

**TAMPA, FL** – A groundbreaking study by University of South Florida (USF) Health researchers has revealed a strong link between ultra-processed foods and colorectal cancer. The research, conducted in partnership with the TGH Cancer Institute, analyzed tumor samples to demonstrate how these foods contribute to chronic inflammation, a key driver of the disease.

The study, led by USF Health Morsani College of Medicine associate professor Ganesh Halade and Dr. Timothy Yeatman, identified numerous molecules derived from processed foods within the tumors. These included foods such as ice cream, sausages, chips, mass-produced bread, breakfast cereals, doughnuts, carbonated drinks, instant soups, and some alcoholic beverages. “We were surprised to see the majority of molecules came from processed food,” stated Dr. Halade. This discovery marks a significant “a-ha” moment in understanding the disease’s etiology.

The research involved meticulous sample handling due to the light sensitivity of the lipid molecules extracted from the tumors, which are stored at -80 degrees Celsius. Utilizing state-of-the-art technology, the team separated and analyzed these molecules, identifying those contributing to inflammation.

This research has profound implications for future therapies. Dr. Halade believes these findings could lead to new treatments not only for colorectal cancer but also other chronic inflammatory diseases. He emphasized that while diet is a crucial factor, maintaining a healthy lifestyle, including adequate sleep and regular exercise, is equally important. Previous USF Health Heart Institute studies have linked imbalanced diets to various health problems, including Alzheimer’s, diabetes, and cardiovascular diseases. The researchers suggest focusing on unprocessed foods such as crab, salmon, spinach, and grass-fed meats as part of a balanced diet.

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