Thu Mar 20 10:31:49 UTC 2025: ## IISc Scientists Develop Needle-Free Blood Glucose Monitoring Technology
**Bengaluru, March 20, 2025** – Researchers at the Indian Institute of Science (IISc) have developed a groundbreaking non-invasive method for measuring blood glucose levels, potentially eliminating the need for painful finger-prick tests for diabetics. The technique, detailed in a study published in *Science Advances*, utilizes photoacoustic sensing.
This innovative approach employs a laser beam shone on the skin. The absorption of light by tissue creates subtle vibrations, detected as ultrasonic sound waves. Crucially, different molecules absorb light differently, creating unique acoustic “fingerprints.” The researchers leveraged this to measure glucose concentrations by analyzing how polarized light interacts with the molecule, affecting the intensity of the emitted sound waves.
The study demonstrated accurate glucose measurement in water, serum, and animal tissue samples at various depths. The non-invasive nature of the technology, coupled with the minimal scattering of sound waves within tissue, ensures accurate readings, even at deeper levels. The IISc team believes this technology offers a significant improvement over current methods, minimizing discomfort and infection risks associated with repeated needle pricks. Further research is expected to refine the technology for clinical application.
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