Sat Oct 11 18:40:00 UTC 2025: Okay, here’s a summarized news article based on the provided text:

**News Article:**

**Iowa State Cyclones Face Colorado Buffaloes in First Matchup in Over a Decade**

BOULDER, CO – The Iowa State Cyclones will travel to Boulder this Saturday to take on the Colorado Buffaloes in their first meeting since 2010. The two teams, former conference rivals in the Big Seven/Eight/12, have a long history, with Colorado holding a dominant 48-16-1 series lead.

However, with Colorado’s departure to the Pac-12 in 2011, the rivalry went on hiatus. Now, the Cyclones, coming off a loss to Cincinnati and currently a 2.5-point favorite according to FanDuel Sportsbook, look to reignite the series against a struggling Colorado team.

The Buffaloes, currently 2-4 (0-3 in Big 12 play), are searching for offensive consistency after losing key players. They’ve been switching quarterbacks, most recently using Liberty transfer Kaidon Salter, who threw four interceptions in the last two games. The team has struggled to score against Power 4 opponents, not exceeding 21 points in any of those games.

Kickoff is set for Saturday. Tickets are still available through Colorado. Fans can catch pre-game coverage on KCCI’s “Big College Kickoff” show streaming on Very Local at 10:30 a.m. KCCI and Very Local may receive a commission for purchases made through links provided.

**Summary of Text**

Iowa State will play Colorado for the first time in more than a decade. The two teams have a long history in the Big 7/8/12 conferences, and Colorado leads the all-time series 48-16-1. However, Colorado left for the Pac-12 in 2011, ending the annual matchup. This year, Colorado is struggling with a 2-4 record and quarterback issues, while Iowa State is coming off a loss and is favored by 2.5 points. The game is set for Saturday, and tickets are available through Colorado. KCCI will have pre-game coverage on Very Local.

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