Sun Oct 26 18:20:00 UTC 2025: ## 49ers Navigating Injury Storm, Eye Trade Deadline as Aiyuk Nears Return

SAN FRANCISCO, CA – Despite a rash of injuries to key players, the San Francisco 49ers (5-2) remain tied for the NFC West lead. The team has been grappling with significant setbacks, including a season-ending ACL tear to star pass rusher Nick Bosa in Week 3 and a potentially season-ending ankle injury to star linebacker Fred Warner in Week 6. Most recently, offseason acquisition Bryce Huff is sidelined with a hamstring injury.

General Manager John Lynch is reportedly exploring the trade market for defensive line reinforcements, despite previously downplaying the need after Warner’s injury. While Lynch has stated that the team “doesn’t have to” make a move, he admitted to KNBR radio that the 49ers would pull the trigger if the right opportunity arises. “If it can help our team we won’t hesitate to do it. But nothing has presented itself that aligns completely to this point,” Lynch said.

With the NFL trade deadline approaching on November 4th, discussions around the league are expected to intensify. ESPN’s Jeremy Fowler reports that teams with valuable pass rushers are seeking significant compensation, while potential buyers are hoping prices will decrease in the coming days. This suggests a potentially late-developing market for edge rushers.

Amidst the injury concerns, the 49ers received positive news regarding wide receiver Brandon Aiyuk, who suffered ACL and MCL tears in Week 7. Head Coach Kyle Shanahan recently indicated that Aiyuk could begin practicing this week, potentially paving the way for a November return. The team will have a 21-day window once Aiyuk’s practice is opened to activate him or place him on injured reserve for the season.

While Bosa is confirmed to be out for the remainder of the season, there is hope that Warner could return for the playoffs, should the 49ers qualify.

Read More