Sun Sep 28 13:10:00 UTC 2025: ## Fantasy Football Frenzy: Key Inactives and Injury Updates for Week 4

**Fantasy Football managers are scrambling as NFL teams release their official inactive lists and injury updates just hours before kickoff.** This week presents a particularly challenging landscape with a number of key players facing injury concerns.

**Early Game Shocker:** Jaylen Warren (RB, PIT) is out with a knee injury after being added to the injury report late Friday. Kenneth Gainwell is expected to start.

**Notable Inactives and Uncertainties:**

* **Carolina Panthers:** Chuba Hubbard (RB) expected to play, Xavier Legette (WR) is out (David Moore will step in), Ja’Tavion Sanders (TE) is out, and Tetairoa McMillan (WR) is expected to suit up.
* **Tampa Bay Buccaneers:** Baker Mayfield (QB) is expected to start despite a biceps injury and Mike Evans (WR) is out (rookie WR Emeka Egbuka’s emergence makes Evans’ continued absence tolerable for Tampa Bay fans, though perhaps not for fantasy managers who drafted Evans.). Chris Godwin Jr., WR will make his 2025 debut in Week 4
* **Dallas Cowboys:** CeeDee Lamb (WR) is out.
* **Indianapolis Colts:** Alec Pierce (WR) is out with a concussion (Adonai Mitchell to step into his role).
* **Minnesota Vikings:** J.J. McCarthy (QB) is out with an ankle injury (Carson Wentz to start).
* **New York Giants:** Graham Gano (K) is on IR (Jude McAtamney to take over), Tyrone Tracy Jr. (RB) is out (Cam Skattebo to take over No. 1 RB duties).
* **Los Angeles Chargers:** Will Dissly (TE) is out (Oronde Gadsden II could step up again).
* **Baltimore Ravens:** Isaiah Likely (TE) is expected to play (may impact Mark Andrews’ fantasy value).
* **Chicago Bears:** D’Andre Swift (RB) is expected to play, Colston Loveland (TE) is out (Cole Kmet the primary target).
* **Jacksonville Jaguars:** Dyami Brown (WR) has a chance to suit up.
* **Los Angeles Rams:** Tyler Higbee (TE) and Colby Parkinson (TE) are questionable (Terrance Ferguson or Davis Allen might benefit); Davante Adams (WR) likely to play.
* **Las Vegas Raiders:** Michael Mayer (TE) is out (Brock Bowers could see more targets).
* **San Francisco 49ers:** Mac Jones (QB) is out with a knee injury(Brock Purdy has indeed been cleared to play, so the timing of Jones’ injury is pretty fortuitous for the 49ers); Jauan Jennings (WR) and Ricky Pearsall (WR) questionable.

**Fantasy managers are urged to refresh their browsers frequently for the latest updates and adjust lineups accordingly.** Consider these updates carefully when making your start/sit decisions this week.

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