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**San Francisco 49ers Face Arizona Cardinals in NFC West Showdown**

**SANTA CLARA, CA –** An undefeated clash is set for Levi’s Stadium this Sunday as the San Francisco 49ers (2-0) host the Arizona Cardinals (2-0) in a crucial NFC West divisional battle. Kickoff is scheduled for 4:25 p.m. ET, and the game will be broadcast on Fox.

Both teams enter the game with perfect records, but neither has dominated their opponents. The 49ers secured a narrow 17-14 victory over the Seattle Seahawks in Week 1 and followed it up with a tight five-point win against the New Orleans Saints. The Cardinals, similarly, have squeaked by against weaker opposition, also defeating the Saints and edging out the Carolina Panthers by five points last week.

The 49ers will be without starting quarterback Brock Purdy, who is sidelined with turf toe. Mac Jones will be at the helm, with Jones showing flashes of potential last week, throwing for 279 yards, three touchdowns, and no interceptions. However, Jones’ history of turnovers from his tenures with the New England Patriots and Jacksonville Jaguars remains a concern. The 49ers will also be missing key offensive players, including tight end George Kittle (hamstring) and wide receiver Brandon Aiyuk (knee).

This game features a battle of quarterbacks: Mac Jones and Kyler Murray. Both had high expectations when their respective careers began, but neither have had much consistency or success in the league.

This game holds significant weight in the NFC West race, particularly with the Los Angeles Rams facing a tough challenge against the Philadelphia Eagles. A win for either the 49ers or Cardinals could grant them sole possession of first place in the division.

Oddsmakers currently favor the 49ers by three points. The over/under is set at 43.5 points.

**Injury Report:**

* **49ers:** Brock Purdy (QB, Turf Toe) – Out, George Kittle (TE, Hamstring) – Out, Brandon Aiyuk (WR, Knee) – Out until after Week 4.

**Where to Watch:**

* **TV:** Fox
* **Streaming:** fubo+
* *If not listed, please contact your TV provider.*

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