Tue Sep 16 05:00:00 UTC 2025: **NFL Week 3 Preview: AFC East Rivalry Kicks Off a Slate of Intriguing Matchups**

**[City, State] –** Week 3 of the NFL season promises a series of captivating matchups, starting with a Thursday Night Football clash between AFC East rivals as the Buffalo Bills (2-0) host the Miami Dolphins (0-2). The Bills, fresh off a dominant Week 2 victory, are heavily favored (-13.5) against a struggling Dolphins team.

Sunday’s schedule is highlighted by two games featuring undefeated teams. The Philadelphia Eagles (2-0) will host the Los Angeles Rams (1-1), while the San Francisco 49ers (2-0) will welcome the Arizona Cardinals (1-1).

Sunday Night Football presents a different scenario, as the winless New York Giants (0-2) travel to face the also-winless Kansas City Chiefs (0-2) in a battle of teams looking to turn their seasons around.

The week concludes with a Monday Night Football showdown between the Detroit Lions (1-1) and the Baltimore Ravens (2-0).

[News Organization] is providing all the odds, as of publication time and provided by ESPN BET, for all the Week 3 games, with analysis powered by ESPN’s Football Power Index (FPI).

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