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**Indian Astronaut Shubhanshu Shukla Conducts Key Experiments on ISS, Advancing Bone Health and Space Exploration**

**New Delhi – July 5, 2025** – Indian astronaut Shubhanshu Shukla, currently aboard the International Space Station (ISS) as part of the Axiom-4 mission, has been actively engaged in critical scientific experiments, according to updates from both Axiom Space and the Indian Space Research Organisation (ISRO).

Shukla, call sign “Shux” and mission pilot, dedicated Saturday to understanding how bones react to microgravity. This research, part of the “Bone on ISS” experiment, aims to identify biological markers related to bone formation and deterioration. Researchers are developing a digital twin – a virtual model simulating bone response to spaceflight – to personalize astronaut health screenings and predict skeletal risks. The findings hold potential for improving osteoporosis treatments on Earth.

ISRO confirmed Shukla’s successful completion of a microgravity experiment involving tardigrades, focusing on their survival, reproduction, and resilience in space. This study could unlock insights into the biological mechanisms of extremophiles and offer therapeutic applications.

Beyond bone health, Shukla is participating in an experiment to monitor radiation exposure on the ISS, crucial for protecting astronauts on longer space missions. He has also deployed samples for the Space Micro Algae investigation, researching the potential of these organisms to provide food, fuel, and breathable air in space.

Other Indian experiments are underway, focusing on microalgae and cyanobacteria for regenerative life-support systems and crew nutrition. As part of the Electronic Displays human-research study, Shukla is performing cognitive and interface assessments to optimize crew interaction with digital systems.

The Axiom-4 mission, a 14-day sojourn to the ISS, is expected to provide valuable data for ISRO’s Gaganyaan mission. Shukla and his crewmates, including veteran US astronaut Peggy Whitson, Hungarian Tibor Kapu, and Polish astronaut Slawosz Uznanski-Wisniewski, will interact with Axiom Space chief scientist Lucie Low on Sunday to discuss progress on the 60 planned science experiments.

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