Sun Jun 29 08:06:17 UTC 2025: **Summary:**

Group Captain Shubhanshu Shukla of India has begun conducting research on the International Space Station (ISS) as part of the Axiom-4 mission. He is primarily focused on microgravity research, including experiments to understand muscle degradation and cerebral hemodynamics in space. ISRO has shortlisted seven microgravity research experiments proposed by Indian (PIs) from various national R&D laboratories and academic institutions which Group Captain Shukla would be conducting during his 14-day stay at the ISS.These experiments aim to benefit both astronauts and individuals on Earth suffering from related medical conditions. The mission also involves joint research initiatives between ISRO and NASA, contributing to a broader understanding of space-related challenges and advancing scientific knowledge.
The Axiom-4 mission research complement includes around 60 scientific studies and activities representing 31 countries, including the U.S., India, Poland, Hungary, Saudi Arabia, Brazil, Nigeria, UAE, and nations across Europe.

**News Article:**

**Indian Astronaut Embarks on Crucial Research Aboard International Space Station**

**Bengaluru, June 30, 2025:** Group Captain Shubhanshu Shukla has commenced his research activities aboard the International Space Station (ISS), marking a significant milestone in India’s space program. As part of the Axiom-4 mission, Group Captain Shukla is deeply involved in multiple experiments, including the study of skeletal muscle degradation and cerebral hemodynamics under microgravity conditions.

“This study aims to uncover the biological pathways behind skeletal muscle degradation in space—a major challenge for astronauts. By identifying these mechanisms, researchers hope to develop targeted therapies that could not only protect space travelers but also aid people suffering from muscle-degenerative diseases on Earth,” said Axion Space.

These investigations, selected by ISRO, involve collaboration with various national research institutions and academic bodies in India. ISRO has shortlisted seven microgravity research experiments proposed by Indian (PIs) from various national R&D laboratories and academic institutions which Group Captain Shukla would be conducting during his 14-day stay at the ISS. Myogenesis is one of the them which has been proposed by the Bengaluru based Institute of Stem Cell Science and Regenerative Medicine (InStem).

The mission isn’t limited to Indian endeavors; it also encompasses joint science investigations and demonstrations with NASA, showcasing international cooperation in space exploration. The knowledge gained from these experiments has the potential to improve medical treatments for muscle-degenerative diseases and cardiovascular conditions on Earth.

The Axiom-4 mission features research from over 30 countries, demonstrating its global impact on scientific advancements. Group Captain Shukla’s work is expected to significantly contribute to ISRO’s microgravity research ecosystem and enhance India’s role in future space endeavors.

Published – June 29, 2025 01:36 pm IST
space programme / space programme
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