Fri Sep 06 23:58:58 UTC 2024: A 17-year-old boy presents with diffuse targetoid and bullous lesions on his extremities and trunk, mucositis, and ocular discharge. He is diagnosed with erythema multiforme (EM), a distinct disorder commonly triggered by infections like herpes simplex virus or medications. Treatment includes topical corticosteroids, antihistamines, and antiviral prophylaxis. In severe cases, immunosuppressants like mycophenolate mofetil may be used. The patient showed improvement with MMF after initial treatment failed. Recurrent EM is more common in older children and male patients, with herpes simplex virus being a common trigger. A skin biopsy can help confirm the diagnosis of EM, which may be confused with other conditions like bullous pemphigoid or fixed drug eruption.

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